Hemolysin Gene Expression in the hns Knockout Mutant of Klebsiella pneumoniae UN Strain
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Han, Jang Suk | - |
dc.contributor.author | Jang, In-Young | - |
dc.contributor.author | Ryu, Hyung-Seok | - |
dc.contributor.author | Kim, Woo-Yeon | - |
dc.date.available | 2019-05-30T00:57:16Z | - |
dc.date.issued | 2010-08 | - |
dc.identifier.issn | 1738-2203 | - |
dc.identifier.issn | 2234-344X | - |
dc.identifier.uri | https://scholarworks.bwise.kr/cau/handle/2019.sw.cau/22313 | - |
dc.description.abstract | Hemolysin proteins are exotoxins produced by bacteria that can cause lysis of red blood cells in vitro. Hemolysin E is a pore-forming hemolysin, one of three types of hemolysin. Generally, hemolysin E is not expressed under standard growth condition's such as growth in LB medium at 37 degrees C. However, in E. coli, when the hns gene, which encodes H-NS, a global regulatory DNA binding protein, is knocked out, hemolysin E gene is expressed. Because hns genes in E. coli and K. pneumoniae are similar, K pneumoniae UN strain hns gene was knocked out in this research. The hns knockout mutant of K. pneumoniae UN is found to produce a 19 kDa hemolysin protein and shows hemolytic activity. | - |
dc.format.extent | 6 | - |
dc.language | 영어 | - |
dc.language.iso | ENG | - |
dc.publisher | KOREAN SOC APPLIED BIOLOGICAL CHEMISTRY | - |
dc.title | Hemolysin Gene Expression in the hns Knockout Mutant of Klebsiella pneumoniae UN Strain | - |
dc.type | Article | - |
dc.identifier.doi | 10.3839/jksabc.2010.062 | - |
dc.identifier.bibliographicCitation | JOURNAL OF THE KOREAN SOCIETY FOR APPLIED BIOLOGICAL CHEMISTRY, v.53, no.4, pp 401 - 406 | - |
dc.identifier.kciid | ART001478563 | - |
dc.description.isOpenAccess | N | - |
dc.identifier.wosid | 000283809900002 | - |
dc.identifier.scopusid | 2-s2.0-78049380458 | - |
dc.citation.endPage | 406 | - |
dc.citation.number | 4 | - |
dc.citation.startPage | 401 | - |
dc.citation.title | JOURNAL OF THE KOREAN SOCIETY FOR APPLIED BIOLOGICAL CHEMISTRY | - |
dc.citation.volume | 53 | - |
dc.type.docType | Article | - |
dc.publisher.location | 대한민국 | - |
dc.subject.keywordAuthor | hemolysin | - |
dc.subject.keywordAuthor | H-NS | - |
dc.subject.keywordAuthor | Klebsiella pneumoniae UN | - |
dc.subject.keywordPlus | GRAM-NEGATIVE BACTERIA | - |
dc.subject.keywordPlus | ESCHERICHIA-COLI K-12 | - |
dc.subject.keywordPlus | H-NS | - |
dc.subject.keywordPlus | PROTEINS | - |
dc.subject.keywordPlus | PATHOGENICITY | - |
dc.subject.keywordPlus | CYTOLYSINS | - |
dc.relation.journalResearchArea | Food Science & Technology | - |
dc.relation.journalWebOfScienceCategory | Food Science & Technology | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.description.journalRegisteredClass | kci | - |
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