A Case of Recurrent Pancreatitis Induced by Trimethoprim-Sulfamethoxazole Re-Exposure
- Authors
- Park, Tae Young; Oh, Hyoung-Chul; Do, Jae Hyuk
- Issue Date
- 30-Jun-2010
- Publisher
- EDITORIAL OFFICE GUT & LIVER
- Keywords
- Pancreatitis; Drug; Ttrimethoprim-sulfamethoxazole
- Citation
- GUT AND LIVER, v.4, no.2, pp 250 - 252
- Pages
- 3
- Journal Title
- GUT AND LIVER
- Volume
- 4
- Number
- 2
- Start Page
- 250
- End Page
- 252
- URI
- https://scholarworks.bwise.kr/cau/handle/2019.sw.cau/22369
- DOI
- 10.5009/gnl.2010.4.2.250
- ISSN
- 1976-2283
2005-1212
- Abstract
- A 32-year-old man presented with epigastric pain. He had a previous episode of acute pancreatitis of undetermined cause 2 years earlier. The patient had taken trimethoprim (80 mg) and sulfamethoxazole (400 mg) twice daily because of acute urethritis, 3 days prior to admission. No definite cause of acute pancreatitis could be identified on baseline studies. A thorough history-taking revealed that the patient had an episode of acute pancreatitis while taking trimethoprim (80 mg) and sulfamethoxazole (400 mg) twice daily for 2 weeks for prostatitis prior to the previous admission. Therefore, a cause-and-effect relationship between trimethoprim-sulfamethoxazole (TMP-SMX) and repeated episodes of pancreatitis was highly suggested. The patient was presumably diagnosed as TMP-SMX-induced pancreatitis. The final diagnosis was TMP-SMX-induced pancreatitis. Since drugs are rare causes of acute pancreatitis and the diagnosis of drug-induced pancreatitis is difficult to establish, we report this interesting case along with a review of medical literature. (Gut Liver 2010;4:250-252)
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