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The Chemopreventive Potential and Anti-inflammatory Activities of Korean Black Ginseng in Colon26-M3.1 Carcinoma Cells and Macrophages
- Authors
- Kim, Ae-Jung; Kang, Shin-Jyung; Lee, Kyung-Hee; Lee, Myungsook; Ha, Sang-Do; Cha, Youn-Soo; Kim, Sun Yeou
- Issue Date
- Feb-2010
- Publisher
- KOREAN SOC APPLIED BIOLOGICAL CHEMISTRY
- Keywords
- black ginseng; colon26-M3.1 carcinoma cells; cytokines; white ginseng
- Citation
- JOURNAL OF THE KOREAN SOCIETY FOR APPLIED BIOLOGICAL CHEMISTRY, v.53, no.1, pp 101 - 105
- Pages
- 5
- Journal Title
- JOURNAL OF THE KOREAN SOCIETY FOR APPLIED BIOLOGICAL CHEMISTRY
- Volume
- 53
- Number
- 1
- Start Page
- 101
- End Page
- 105
- ISSN
- 1738-2203
2234-344X
- Abstract
- We investigated the chemopreventive and anti-inflammatory activity of Korean black ginseng (BG) in colon26-M3.1 carcinoma cells and macrophages (in vitro) compared with white ginseng (WG). Both WC and BC had no significant inhibitory effect on normal splenocytes, but on colon26-M3.1 carcinoma cells, BC showed significantly greater inhibitory effect than that of WG. Treating with either WG or BC extracts, the release of TNF-alpha was significantly decreased in response to lipopolysaccharide as compared with untreated control.
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