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Total intravenous anesthesia with propofol and remifentanil in a patient with MELAS syndrome -A case reportTotal intravenous anesthesia with propofol and remifentanil in a patient with MELAS syndrome -A case report-
- Authors
- Park, J.S.; Baek, C.W.; Kang, H.; Cha, S.M.; Park, J.W.; Jung, Y.H.; Woo, Y.-C.
- Issue Date
- Apr-2010
- Publisher
- 대한마취통증의학회
- Keywords
- Atracurium; General anesthesia; Melas syndrome; Propofol; Remifentanil; TIVA
- Citation
- Korean Journal of Anesthesiology, v.58, no.4, pp 409 - 412
- Pages
- 4
- Journal Title
- Korean Journal of Anesthesiology
- Volume
- 58
- Number
- 4
- Start Page
- 409
- End Page
- 412
- ISSN
- 2005-6419
2005-7563
- Abstract
- A 23-year-old woman with MELAS (mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke-like episodes) underwent a laparoscopy-assisted appendectomy. MELAS syndrome is a multisystemic disease caused by mitochondrial dysfunction. General anesthesia has several potential hazards to patients with MELAS syndrome, such as malignant hyperthermia, hypothermia, and metabolic acidosis. In this case, anesthesia was performed with propofol, remifentanil TCI, and atracurium without any surgical or anesthetic complications. We discuss the anesthetic effects of MELAS syndrome. Copyright © Korean Society of Anesthesiologists, 2010.
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