Clinical efficacy and tolerance of 1% nadifloxacin cream in the treatment of mild to moderate acne vulgaris in South Korea
DC Field | Value | Language |
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dc.contributor.author | Choi, W.J. | - |
dc.contributor.author | Kim, K.J. | - |
dc.contributor.author | Kim, N.I. | - |
dc.contributor.author | Kye, Y.C. | - |
dc.contributor.author | Suh, D.H. | - |
dc.contributor.author | Lee, J.H. | - |
dc.contributor.author | Kim, M.N. | - |
dc.contributor.author | Lee, E.S. | - |
dc.contributor.author | Lee, J.H. | - |
dc.contributor.author | Ro, Y.S. | - |
dc.date.available | 2019-05-30T02:26:07Z | - |
dc.date.issued | 2010-08 | - |
dc.identifier.issn | 0494-4739 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/cau/handle/2019.sw.cau/22743 | - |
dc.description.abstract | Background: Antimicrobials have been a mainstay of inflammatory acne treatment for more than 30 years. However, antibiotic-resistant propionibacteria had been isolated with increased frequency, and associated with failure to respond to antibiotic therapy. Objective: The aim of this study was to investigate the clinical efficacy and tolerance of 1% nadifloxacin cream. Methods: In the final analysis, 197 patients with mild to moderate facial acne vulgaris were enrolled. The patients were instructed to apply 1% nadifloxacin cream twice daily to the affected skin after washing the face. Following 2 and 4 weeks of treatment, patients were observed for clinical response: number of the acne lesions, Korea acne grading system (KAGS), global improvement, and occurrence of adverse reactions. Results: During 4 weeks of treatment, nadifloxacin caused significant reduction in the number of inflamed papulo-pustular lesions and open/closed comedones. In addition, significant reduction of KAGS was observed. About 96% of patients showed clinical improvement in the overall evaluation of the therapeutic effect by physicians. All reported adverse events were mild. Conclusion: This study shows that 1% nadifloxacin cream can be an effective and safe treatment for mild to moderate acne vulgaris. | - |
dc.format.extent | 7 | - |
dc.language | 한국어 | - |
dc.language.iso | KOR | - |
dc.publisher | 대한피부과학회 | - |
dc.title | Clinical efficacy and tolerance of 1% nadifloxacin cream in the treatment of mild to moderate acne vulgaris in South Korea | - |
dc.title.alternative | Clinical Efficacy and Tolerance of 1% Nadifloxacin Cream in the Treatment of Mild to Moderate Acne Vulgaris in South Korea | - |
dc.type | Article | - |
dc.identifier.bibliographicCitation | Korean Journal of Dermatology, v.48, no.8, pp 665 - 671 | - |
dc.identifier.kciid | ART001476922 | - |
dc.description.isOpenAccess | N | - |
dc.identifier.scopusid | 2-s2.0-79960902781 | - |
dc.citation.endPage | 671 | - |
dc.citation.number | 8 | - |
dc.citation.startPage | 665 | - |
dc.citation.title | Korean Journal of Dermatology | - |
dc.citation.volume | 48 | - |
dc.type.docType | Article | - |
dc.publisher.location | 대한민국 | - |
dc.subject.keywordAuthor | 1% nadifloxacin cream | - |
dc.subject.keywordAuthor | Acne | - |
dc.subject.keywordAuthor | Treatment | - |
dc.description.journalRegisteredClass | scopus | - |
dc.description.journalRegisteredClass | kci | - |
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