Brain Factor-7 Extracted from Bombyx mori Enhances Cognition and Attention in Normal Children
- Authors
- Kim, Kunwoo; Park, Subin; Yoo, Hanik K.; Lee, Jun-Young; Jung, Hee-Yeon; Kim, Do-Hee; Lee, Hyun-Jung; Kim, Jin-Young; Youn, Young-Chul; Marshall, Maurice R.; Kim, Sung-Su; Jeong, Yoonhwa
- Issue Date
- Jun-2009
- Publisher
- MARY ANN LIEBERT, INC
- Keywords
- attention; brain factor-7; children; cognition; Color Trails Making Test; learning and memory
- Citation
- JOURNAL OF MEDICINAL FOOD, v.12, no.3, pp 643 - 648
- Pages
- 6
- Journal Title
- JOURNAL OF MEDICINAL FOOD
- Volume
- 12
- Number
- 3
- Start Page
- 643
- End Page
- 648
- URI
- https://scholarworks.bwise.kr/cau/handle/2019.sw.cau/23149
- DOI
- 10.1089/jmf.2008.1236
- ISSN
- 1096-620X
1557-7600
- Abstract
- It has been reported that brain factor-7 (BF-7) extracted from Bombyx mori improves cognitive functions in normal juveniles and adults as well as cognitively impaired patients. Clinical studies with normal children evaluated the role of BF-7 on brain function in these patients. The objective of this study was to improve cognitive functions of normal schoolchildren with BF-7. Forty-six normal healthy children were divided into two treatment groups: BF-7 (9.9 +/- 1.18 years old; 9 boys, 14 girls) and placebo (9.8 +/- 1.03 years old; 10 boys, 13 girls). The Color Trails Making Test was used to measure the efficacy of BF-7 on cognition and attention. Results showed that BF-7 reduced the response time by an average of 23% for the Color Trails Making Test. Moreover, BF-7 improved the accuracy of the task around twofold. The results reveal that BF-7 improves brain function for attention and cognitive flexibility in children.
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