Exposure to extremely low frequency magnetic fields enhances locomotor activity via activation of dopamine D-1-like receptors in mice
DC Field | Value | Language |
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dc.contributor.author | Shin, Eun-Joo | - |
dc.contributor.author | Jeong, Ji Hoon | - |
dc.contributor.author | Kim, Hyun Ji | - |
dc.contributor.author | Jang, Choon-Gon | - |
dc.contributor.author | Yamada, Klyofumi | - |
dc.contributor.author | Nabeshima, Toshitaka | - |
dc.contributor.author | Kim, Hyoung-Chun | - |
dc.date.available | 2019-05-30T05:37:48Z | - |
dc.date.issued | 2007-12 | - |
dc.identifier.issn | 1347-8613 | - |
dc.identifier.issn | 1347-8648 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/cau/handle/2019.sw.cau/23893 | - |
dc.description.abstract | We demonstrated that exposure to extremely low frequency magnetic fields (ELF-MF) enhanced dopamine levels in the rat striatum. To extend our understanding, we examined the role of dopaminergic receptors in ELF-MF-induced behavioral changes. Exposure to ELF-MF (2.4 mT, 1 h/day, for one or seven days) enhanced locomotor activity in a time-dependent manner. This hyperlocomotor activity paralleled an increase in c-Fos-like immunoreactivity (c-Fos-IR). Pretreatment with SCH23390, a dopaminergic D-1-like receptor antagonist, but not with sulpiride, a. dopaminergic D-2-like receptor antagonist, inhibited ELF-MF-induced increased locomotor activity and c-Fos-IR. Thus, our results suggest that ELF-MF-induced behavioral responses are, at least in part, mediated by activation of dopamine D-1-like receptors. | - |
dc.format.extent | 5 | - |
dc.language | 영어 | - |
dc.language.iso | ENG | - |
dc.publisher | JAPANESE PHARMACOLOGICAL SOC | - |
dc.title | Exposure to extremely low frequency magnetic fields enhances locomotor activity via activation of dopamine D-1-like receptors in mice | - |
dc.type | Article | - |
dc.identifier.doi | 10.1254/jphs.SC0070348 | - |
dc.identifier.bibliographicCitation | JOURNAL OF PHARMACOLOGICAL SCIENCES, v.105, no.4, pp 367 - 371 | - |
dc.description.isOpenAccess | N | - |
dc.identifier.wosid | 000251993900008 | - |
dc.identifier.scopusid | 2-s2.0-37549053264 | - |
dc.citation.endPage | 371 | - |
dc.citation.number | 4 | - |
dc.citation.startPage | 367 | - |
dc.citation.title | JOURNAL OF PHARMACOLOGICAL SCIENCES | - |
dc.citation.volume | 105 | - |
dc.type.docType | Article | - |
dc.publisher.location | 일본 | - |
dc.subject.keywordAuthor | extremely low frequency magnetic field | - |
dc.subject.keywordAuthor | locomotor activity | - |
dc.subject.keywordAuthor | dopaminergic receptor | - |
dc.subject.keywordPlus | ELECTROMAGNETIC-FIELDS | - |
dc.subject.keywordPlus | FOS EXPRESSION | - |
dc.subject.keywordPlus | RATS | - |
dc.subject.keywordPlus | STIMULATION | - |
dc.subject.keywordPlus | STRIATUM | - |
dc.subject.keywordPlus | BEHAVIOR | - |
dc.relation.journalResearchArea | Pharmacology & Pharmacy | - |
dc.relation.journalWebOfScienceCategory | Pharmacology & Pharmacy | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
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