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Enhanced biodegradation of environmental allergen by a vgb-containing Burkholderia cepacia

Authors
Kim, Mi SunYoon, Suk-RanJun, WoojinPark, So-YoungYang, YoungShim, Sang InHwang, Kwang WooChung, Jin Woong
Issue Date
Dec-2005
Publisher
KOREAN SOC TOXICOGENOMICS & TOXICOPROTEOMICS
Keywords
biodegradation; environmental allergen; benzoic acid; bacterial hemoglobin
Citation
MOLECULAR & CELLULAR TOXICOLOGY, v.1, no.4, pp 262 - 267
Pages
6
Journal Title
MOLECULAR & CELLULAR TOXICOLOGY
Volume
1
Number
4
Start Page
262
End Page
267
URI
https://scholarworks.bwise.kr/cau/handle/2019.sw.cau/24456
ISSN
1738-642X
Abstract
Using genetic engineering, the Vitreoscilla (bacterial) hemoglobin gene (vgb) was integrated stably into the chromosomes of and Burkholderia cepacia. Similar to previous results, the wild type VHb improved growth for Burkholderia cepacia and degradation of benzoic acid under both normal and low aeration conditions. The stable expression of VHb enhanced these parameters. The results demonstrate the possibility that the positive effects provided by VHb may be augmented by protein engineering.
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대학원 (글로벌혁신신약학과)
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