Bioequivalence trials with the incomplete 3X3 crossover design
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Lim, N.K. | - |
dc.contributor.author | Park, Sang-Gue | - |
dc.contributor.author | Stanek, E | - |
dc.date.available | 2019-05-30T07:36:26Z | - |
dc.date.issued | 2005-10 | - |
dc.identifier.issn | 0323-3847 | - |
dc.identifier.issn | 1521-4036 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/cau/handle/2019.sw.cau/24517 | - |
dc.description.abstract | In bioequivalence trials, one often considers two or more generic products with the original one. The 3 x 3 crossover design can be adopted to evaluate the two generic candidates with a brand name drug, rather than conducting two separate 2 x 2 crossover trials. Dropouts, however, are more likely to occur due to various administrative reasons when we consider a higher order crossover design. A modified method, which was originally given by Chow and Shao (1997), is extended to compare two generic products with a reference in the incomplete 3 x 3 crossover design. A simulation study and discussion are also presented. | - |
dc.format.extent | 9 | - |
dc.language | 영어 | - |
dc.language.iso | ENG | - |
dc.publisher | AKADEMIE VERLAG GMBH | - |
dc.title | Bioequivalence trials with the incomplete 3X3 crossover design | - |
dc.type | Article | - |
dc.identifier.doi | 10.1002/bimj.200410144 | - |
dc.identifier.bibliographicCitation | BIOMETRICAL JOURNAL, v.47, no.5, pp 635 - 643 | - |
dc.description.isOpenAccess | N | - |
dc.identifier.wosid | 000232916900004 | - |
dc.identifier.scopusid | 2-s2.0-27844559212 | - |
dc.citation.endPage | 643 | - |
dc.citation.number | 5 | - |
dc.citation.startPage | 635 | - |
dc.citation.title | BIOMETRICAL JOURNAL | - |
dc.citation.volume | 47 | - |
dc.type.docType | Article | - |
dc.publisher.location | 미국 | - |
dc.subject.keywordAuthor | average bioequivalence | - |
dc.subject.keywordAuthor | 3 X 3 crossover design | - |
dc.subject.keywordAuthor | missing data | - |
dc.subject.keywordAuthor | least square estimator | - |
dc.relation.journalResearchArea | Mathematical & Computational Biology | - |
dc.relation.journalResearchArea | Mathematics | - |
dc.relation.journalWebOfScienceCategory | Mathematical & Computational Biology | - |
dc.relation.journalWebOfScienceCategory | Statistics & Probability | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
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