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Antimicrobial activity of native chitosan, degraded chitosan, and O-carboxymethylated chitosan
- Authors
- Kim, KW; Thomas, RL; Lee, C; Park, HJ
- Issue Date
- Aug-2003
- Publisher
- INT ASSOC FOOD PROTECTION
- Citation
- JOURNAL OF FOOD PROTECTION, v.66, no.8, pp 1495 - 1498
- Pages
- 4
- Journal Title
- JOURNAL OF FOOD PROTECTION
- Volume
- 66
- Number
- 8
- Start Page
- 1495
- End Page
- 1498
- ISSN
- 0362-028X
- Abstract
- The antimicrobial activity of native chitosan was compared to that of lipase-degraded chitosan. The effects of O-carboxymethylated (O-CM) substitution on native (molecular weight, 120; degree of deacetylation, 84.71%) and lipase-degraded chitosans were also investigated. The antimicrobial activity of native chitosan was more extensive than that of lipase-degraded chitosan; however, lipase-degraded chitosan was still highly effective and more water-soluble. O-CM chitosan derived from degraded chitosan was more effective than O-CM chitosan derived from native chitosan. O-CM substitution enhanced lipase-degraded chitosan's antimicrobial activity without reducing its solubility.
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