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한국형 양극성 장애 약물치료 알고리듬 2010 : 유지치료Korean Medication Algorithm for Bipolar Disorder 2010 : Maintenance Therapy

Authors
이정구박원명윤보현전덕인김원서정석민경준이은주연호안용민김병수신영철
Issue Date
2011
Publisher
대한우울∙조울병학회
Keywords
Bipolar disorder; Algorithm; Maintenance therapy; Atypical antipsychotics; Mood stabilizer; 양극성 장애; 알고리듬; 유지치료; 비정형 항정신병약물; 기분조절제
Citation
우울조울병, v.9, no.3, pp 162 - 170
Pages
9
Journal Title
우울조울병
Volume
9
Number
3
Start Page
162
End Page
170
URI
https://scholarworks.bwise.kr/cau/handle/2019.sw.cau/27550
ISSN
1738-0960
Abstract
Objective : After announcement of Korean Medication Algorithm Project for Bipolar Disorder (KMAP-BP) in 2006, there has been an increasing need for the revision of treatment algorithm due to rapid changes in the management for bipolar disorder. In this study, we evaluated the maintenance treatment of bipolar I and bipolar II disorders of KMAP-BP 2010. Method : The questionnaire to survey the expert opinion of medication for bipolar disorder was completed by the review committee consisting of 65 experienced psychiatrists. It is composed of 37 questions, and each question includes various sub-items. We classified the expert opinion to 3 categories (the first-line treatment, the second-line, the third-line) by χ2 test. A part of this revision regarding maintenance treatment had 7 items ; 5 on bipolar I and 2 on bipolar II disorder. Results : In case of bipolar I disorder, mood stabilizer monotherapy and combination of mood stabilizer and atypical antipsychotic drugs were 1st-line treatment. In maintenance management for bipolar II disorder, two treatment options were recommended. Treatment with MS alone or combinations of MS and atypical antipsychotic drugs were preferred. Atypical antipsychotic drugs and lamotrigine were more favored in the maintenance treatment for bipolar I and II disorders than previous KAMP-BP 2006. Conclusions : There have been growing body of tendency that atypical antipsychotics are more preferred than the previous KMAP-BP. Also there is an increasing interest on the maintenance use of lamotrigine in the maintenance treatment of bipolar disorder. (J of Kor Soc for Dep and Bip Disorders 2011;9:162-170)
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Min, Kyung Joon
의과대학 (의학부(임상-서울))
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