Label-Free and Real-Time Detection of Avian Influenza Using Nanowire Field Effect Transistors
- Authors
- Ahn, Jae-Hyuk; Im, Maesoon; Park, Tae Jung; Lee, Sang Yup; Choi, Yang-Kyu
- Issue Date
- Sep-2015
- Publisher
- AMER SCIENTIFIC PUBLISHERS
- Keywords
- Real-Time Detection; Label-Free; Avian Influenza; Nanowire; Field Effect Transistor; Biosensor
- Citation
- JOURNAL OF BIOMEDICAL NANOTECHNOLOGY, v.11, no.9, pp 1640 - 1643
- Pages
- 4
- Journal Title
- JOURNAL OF BIOMEDICAL NANOTECHNOLOGY
- Volume
- 11
- Number
- 9
- Start Page
- 1640
- End Page
- 1643
- URI
- https://scholarworks.bwise.kr/cau/handle/2019.sw.cau/27664
- DOI
- 10.1166/jbn.2015.1501
- ISSN
- 1550-7033
1550-7041
- Abstract
- Real-time and label-free detection of antibodies from avian influenza (anti-Al) in an aqueous solution is demonstrated with the use of a nanowire field effect transistor. A real-time measurement system is constructed without leakage paths through the solution medium. The current through the nanowire changes significantly after an injection of an anti-Al solution onto the device, which was previously functionalized by the antigen of Al as a probe of anti-Al. In contrast, no significant response arises when an anti-Al solution is injected onto a non-functionalized device. Therefore, the real-time detection of specific antibody-antigen interaction of the Al is successfully implemented for a chip-based biosensor.
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Collections - College of Natural Sciences > Department of Chemistry > 1. Journal Articles
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