요석의 일회 발생 환자군과 재발 환자군에서 요석대사 위험인자들의 비교Comparison of Metabolic Risk Factors in Patients with First-time and Recurrent Stone Formations
- Authors
- 오승영; 문영태
- Issue Date
- 2004
- Publisher
- 대한비뇨기과학회
- Keywords
- Risk factor; Recurrence; Urolithiasis
- Citation
- Investigative and Clinical Urology, v.45, no.6, pp 551 - 556
- Pages
- 6
- Journal Title
- Investigative and Clinical Urology
- Volume
- 45
- Number
- 6
- Start Page
- 551
- End Page
- 556
- URI
- https://scholarworks.bwise.kr/cau/handle/2019.sw.cau/28692
- ISSN
- 2466-0493
2466-054X
- Abstract
- Purpose: The aim of this study was to determine whether patients with recurrent stone formations have significant metabolic risk factors compared to patients with first-time stone formations.
Materials and Methods: 456 patients who participated in the stone metabolic study at Chung-Ang University Hospital between January 1, 2001 and June 30, 2002 were selected as subjects. 347 patients (211 males, 136 females) with first-time stone formations and 109 patients (77 males, 32 females) with recurrent stone formations were selected. The blood test and 24-hour urine test were categorized and grouped according to: 1) gender; 2) age brackets of 40 and under, 40-49, and 60 and over; 3) and gender-based age bracket distribution.
Results: Hypocitraturia was the most common metabolic abnormality in both males and females and in all age groups. Hypocitraturia, in particular, was shown to have more significant associations (p<0.05) in female patients in their 40s and 50s with recurrent stone formations (75%) compared to female patients of the same age range with first-time stone formations (38.6%). In addition, a small urine volume was found to have similar significant associations with these subject groups (p<0.05) with respect to patients with first-time stone formations and recurrent stone formations. Female Patients (especially those in their 40s and 50s) with recurrent stone formations (242.1±158.5) were found to have a higher probability (p<0.05) of hypocitraturia than patients with first-time stone formation (419.9±242.3).
Conclusions: In women with recurrent stone formation, hypocitraturia and low urine volume are the risk factors that differentiate them from patients with first-time stone formation. The correction of hypocitraturia & low urine volume may significantly reduce the patients’ chances for recurrent stone formation. (Korean J Urol 2004;45:551-556)
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