기능성 식품 복합처방의 항산화 및 항당뇨 효과

Abstract

To investigate the antioxidant activitys of Biofuntional Foods Prescriptions (BFP), we were measured radical scav-enging activity with 1,1-diphenyl-2-picryl-hydrazyl (DPPH) method and anti-lipid peroxidative efficacy on human LDL withthiobarbituric acid reactive substances (TBARS) assay. The DPPH and TBARS assay were revealed that Two BFP had sig-inificantly activity when compared to that of contrast drug. The antidiabetic effect of Dicollow-B (Rx B) were investigated instreptozotocin-induced diabetic Spraque-Dawley (SD) rats. When each 100, 200 kg/mg fraction of Rx B was administrated, theblood glucose showed 155.7 mg/dl, 124.7 mg/dl and inhibitive activity of the serum total cholesterol showed 67.8 mg/dl,61.5 mg/dl and the serum triglyceride of hyperglycemic rats revealed 66.3 mg/dl, 62.3 mg/dl. Those were decreased dose-dependently when compared with control group. The effect of Rx B on The body weight was not dose-dependently decreaseby the administration of 100 mg/kg or 200 mg/kg fractions. But it was dose-dependantly decreased from 22.2 4.9 g to18.9 4.4 g by the administration of 400 mg/kg fraction.