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Bactericidal Activity of Grapefruit (Citrus paradisi) SeedExtract-Based Disinfectant
- Authors
- Han, Jaehong; Kim, Yong-Ung; Kim, Ki-Yeon; Hahm, Young Tae
- Issue Date
- 2006
- Publisher
- 한국응용생명화학회
- Keywords
- Grapefruit seed extract; Bactericidal; Disinfectant; Osmotic shift; KFDA
- Citation
- Journal of Applied Biological Chemistry, v.49, no.3, pp 90 - 94
- Pages
- 5
- Journal Title
- Journal of Applied Biological Chemistry
- Volume
- 49
- Number
- 3
- Start Page
- 90
- End Page
- 94
- ISSN
- 1976-0442
2234-7941
- Abstract
- Bactericidal activity of grapefruit seed extract (GSE)-based disinfectant, as a safe disinfectant, was measured against five bacteria by Korean Food & Drug Administration (KFDA) dilution-neutralization method. GSE-based disinfectant showed a 99.9999% bactericidal activity against Escherichia coli ATCC 10536, Salmonella typhi ATCC 29629, Staphylococcus aureus ATCC 6538 , Bacillus cereus ATCC 11778, and Listeria monocytogenes ATCC 1911 at the concentration of 2.15% GSE. It showed better bactericidal activity against Gram-negative bacteria of E. coli ATCC 10536 and S. typhi ATCC 29629 at lower concentration of GSE (0.43%). Based on the results, it was suggested that a possible bactericidal mechanism of GSE active ingredients was due to the abrupt osmotic shift during the bactericidal activity test by KFDA method
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