Central Nervous System Involvement of Acute Lymphoblastic Leukemia
- Authors
- 현승재; 김영백; 유현; 홍현종
- Issue Date
- 2006
- Publisher
- 대한신경외과학회
- Keywords
- Leukemia· Burkitt’s lymphoma· Spine· Laminectomy.
- Citation
- 대한신경외과학회지, v.40, no.1, pp 54 - 57
- Pages
- 4
- Journal Title
- 대한신경외과학회지
- Volume
- 40
- Number
- 1
- Start Page
- 54
- End Page
- 57
- URI
- https://scholarworks.bwise.kr/cau/handle/2019.sw.cau/28987
- ISSN
- 1225-8245
1598-7876
- Abstract
- Central nervous system(CNS) involvement of acute lymphoblastic leukemia may occur. However, CNS involvement as a first manifestation of leukemia is very rare. An 8-year-old girl complained of a backache after playing in the water. Neurological examination detected progressing paraparesis. Magnetic resonance imaging(MRI) of the thoracolumbar spine showed a well-circumscribed homogeneous posterior extradural mass lesion extending from T7 to T9. MRI of the brain showed diffused fatty marrow replacement of the calvarium and the skull base. We report a patient with epidural Burkitt’s lymphoma of the thoracic and lumbar vertebra causing compression of the spinal cord after pathologic evaluation. The tumor consisted mainly of lymphoblastic cells, which were identical to those originally seen in the bone marrow aspiration and biopsy. After decompressive laminectomy she began consolidation chemotherapy.
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