해양칠게 혈림프로부터 렉틴의 분리 및 당 결합특성Isolation and Carbohydrate Binding Specificity of a Lectin from the Hemolymph of Coastal CrabMacrophthalmus Japonicus
- Authors
- 김하형; 정우혁; 배찬형; 황광우; 김하형
- Issue Date
- 2006
- Publisher
- 대한약학회
- Keywords
- lectin; crab; sialoglycoprotein
- Citation
- 약 학 회 지, v.50, no.3, pp 166 - 171
- Pages
- 6
- Journal Title
- 약 학 회 지
- Volume
- 50
- Number
- 3
- Start Page
- 166
- End Page
- 171
- URI
- https://scholarworks.bwise.kr/cau/handle/2019.sw.cau/29058
- ISSN
- 0377-9556
- Abstract
- the coastal crab Macrophthalmus Japonicus. This lectin, Macrophthalmus Japonicus lectin (MJL), was eluted with 50mM Tris-HCl, 0.3 M NaCl, 10 mM EDTA, and the recovery yield from the crude protein extract was about 5.6%. The molecularweight of MJL was estimated as 65 kDa in SDS-PAGE both under reducing and non-reducing conditions. MJL induced anagglutination reaction in rabbit, rat, and mouse erythrocytes, but not in human ABO types. This activity was effectivelyinhibited by sialoglycoproteins such as fetuin, bovine submaxillary mucin, and thyroglobulin.Keywords . lectin, crab, sialoglycoprotein... .. , .. , .... , ... ... .. , ....
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Collections - College of Pharmacy > School of Pharmacy > 1. Journal Articles
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