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한국형 양극성 장애 약물치료 알고리듬 2006(IV):급속순환형Korean Medication Algorithm for Bipolar Disorder 2006(IV):Rapid Cycling

Authors
전덕인박원명이은윤보현정상근김원신영철조현상권준수서정석하규섭민경준
Issue Date
2006
Publisher
대한정신약물학회
Keywords
양극성 장애; 급속순환형; 한국형 약물치료 알고리듬; 개정; Bipolar disorder; Rapid cycling; Korean medication algorithm; Revision
Citation
대한정신약물학회지, v.17, no.5, pp 449 - 455
Pages
7
Journal Title
대한정신약물학회지
Volume
17
Number
5
Start Page
449
End Page
455
URI
https://scholarworks.bwise.kr/cau/handle/2019.sw.cau/29622
ISSN
1017-5717
2092-5700
Abstract
Objective: The development of treatment guidelines has emerged as an important element so as to standardize treatment and to provide clinicians with algorithms. From the previous publication of Korean Medication Algorithm Project for Bipolar Disorder(KMAP-BP): rapid cycling in 2002, we revised that in 2006. Methods: The questionnaire to survey the expert opinion of medication for rapid cycling was completed by the review committee consisting of 53 experienced Korean psychiatrists. It is composed of 7 questions, and each question includes various options. We classified the expert opinion to 3 categories based on the lowest category in which the confidence interval fell (6.5≤ for first-line and 3.5≤ for second-line treatment). Results: Generally, 'treatment of choice' for rapid cycling was not demonstrated. The first-line treatment is the combination of a mood stabilizer and an atypical antipsychotic. Combination of two mood stabilizers was preferred as next strategy. Divalproex and lithium were the first-line choice as mood stabilizer. Compared to the surveys in 2002, the preference for lamotrigine and atypical antipsychotics has increased while that of carbamazepine and antidepressant has decreased. Conclusion: With the result of the survey, the discussion in executive committee, and the evidences from clinical studies, we have revised KMAP-BP for rapid cycling.
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의과대학 (의학부(임상-서울))
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