한국형 양극성 장애 약물치료 알고리듬 2018 : 총론Korean Medication Algorithm for Bipolar Disorder 2018 : Overview
- Authors
- 김원; 박원명; 윤보현; 전덕인; 서정석; 이정구; 우영섭; 정종현; 김문두; 손인기; 심세훈; 송후림; 민경준
- Issue Date
- 2018
- Publisher
- 대한우울∙조울병학회
- Keywords
- 양극성 장애; 약물치료; 알고리듬; Bipolar disorder; KMAP-BP 2018; Pharmacotherapy; Algorithm
- Citation
- 우울조울병, v.16, no.1, pp 1 - 12
- Pages
- 12
- Journal Title
- 우울조울병
- Volume
- 16
- Number
- 1
- Start Page
- 1
- End Page
- 12
- URI
- https://scholarworks.bwise.kr/cau/handle/2019.sw.cau/2993
- ISSN
- 1738-0960
2671-4655
- Abstract
- Objectives : The Korean Medication Algorithm for Bipolar Disorder (KMAP-BP), which was first published in 2002 and updated in 2006, 2010 and 2014, is revised again through the expert’s consensus of opinion. Methods : Out of eighty-four member of the review committee, sixty-one members completed the survey. We analyzed the answers, and thus discussed the data and held a clinician hearing on the results. Therefore, we report the results of KMAP-BP 2018. Results : The preferred first-step strategies for acute euphoric mania are the combination of mood stabilizer (MS) and atypical antipsychotics (AAP), MS monotherapy and AAP monotherapy. For psychotic mania, combination of MS and AAP, and AAP monotherapy are preferred. The first-step strategies for acute bipolar, mild to moderate, depression are MS monotherapy, lamotrigine (LTG) monotherapy, AAP monotherapy, MS+AAP combination, AAP+LTG combination and MS+LTG combination. For non-psychotic severe depression, the MS+AAP combination, AAP+LTG combination and MS+LTG combination are preferred. For psychotic severe depression, the MS+AAP, AAP+antidepressant (AD) and AAP+LTG are preferred. Conclusion : We surveyed the expert consensus for the treatment of bipolar disorders and developed KMAP-BP 2018. We hope that this KMAPBP 2018 is going to be helpful for clinicians to treat the patients with bipolar disorder.
Objectives : The Korean Medication Algorithm for Bipolar Disorder (KMAP-BP), which was first published in 2002 and updated in 2006, 2010 and 2014, is revised again through the expert’s consensus of opinion. Methods : Out of eighty-four member of the review committee, sixty-one members completed the survey. We analyzed the answers, and thus discussed the data and held a clinician hearing on the results. Therefore, we report the results of KMAP-BP 2018. Results : The preferred first-step strategies for acute euphoric mania are the combination of mood stabilizer (MS) and atypical antipsychotics (AAP), MS monotherapy and AAP monotherapy. For psychotic mania, combination of MS and AAP, and AAP monotherapy are preferred. The first-step strategies for acute bipolar, mild to moderate, depression are MS monotherapy, lamotrigine (LTG) monotherapy, AAP monotherapy, MS+AAP combination, AAP+LTG combination and MS+LTG combination. For non-psychotic severe depression, the MS+AAP combination, AAP+LTG combination and MS+LTG combination are preferred. For psychotic severe depression, the MS+AAP, AAP+antidepressant (AD) and AAP+LTG are preferred. Conclusion : We surveyed the expert consensus for the treatment of bipolar disorders and developed KMAP-BP 2018. We hope that this KMAPBP 2018 is going to be helpful for clinicians to treat the patients with bipolar disorder.
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