RBL 2H3 비만세포에서 히스타민 유리와 칼슘과의 관계
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 박성훈 | - |
dc.contributor.author | 김수정 | - |
dc.contributor.author | 김정민 | - |
dc.contributor.author | 박주현 | - |
dc.contributor.author | 최방실 | - |
dc.contributor.author | 이지윤 | - |
dc.contributor.author | 최미영 | - |
dc.contributor.author | 심상수 | - |
dc.date.available | 2019-07-24T03:57:33Z | - |
dc.date.issued | 2007 | - |
dc.identifier.issn | 0377-9556 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/cau/handle/2019.sw.cau/30242 | - |
dc.description.abstract | To investigate the relation between extracellular Ca2+ and histamine release, we observed agonist-induced his-tamine release from RBL 2H3 mast cells in the presence or absence of extracellular Ca2+ concentration. Histamine releaseinduced by melittin and thapsigargin were greater in the presence of extracellular Ca2+ than in the absence of extracellularCa2+ . Econazole-induced histamine release had nothing to do with extracellular Ca2+ , whereas arachidonic acid-induced his-2+ . Calmodulin antagonists did not affect melittin-induced his-tamine release but they may potentiate arachidonic acid-induced histamine release. These data suggest that arachidonicacid-induced histamine release may be mediated via Ca2+ -independent pathway and may be potentiated by the block ofCa2+ -dependent pathway.Keywords . mast cells, histamine, calcium, calmodulin antagonist..... ....... histamine. ... ... Ca2+ | - |
dc.format.extent | 5 | - |
dc.publisher | 대한약학회 | - |
dc.title | RBL 2H3 비만세포에서 히스타민 유리와 칼슘과의 관계 | - |
dc.title.alternative | Relationship Between Histamine Release and Ca Mobilizaton in RBL 2H3 Mast Cells | - |
dc.type | Article | - |
dc.identifier.bibliographicCitation | 약 학 회 지, v.51, no.1, pp 63 - 67 | - |
dc.identifier.kciid | ART001054848 | - |
dc.description.isOpenAccess | N | - |
dc.citation.endPage | 67 | - |
dc.citation.number | 1 | - |
dc.citation.startPage | 63 | - |
dc.citation.title | 약 학 회 지 | - |
dc.citation.volume | 51 | - |
dc.publisher.location | 대한민국 | - |
dc.subject.keywordAuthor | mast cells | - |
dc.subject.keywordAuthor | histamine | - |
dc.subject.keywordAuthor | calcium | - |
dc.subject.keywordAuthor | calmodulin antagonist | - |
dc.description.journalRegisteredClass | kci | - |
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