대나무 추출액의 항산화 작용과 미백작용Anti-oxidant Activity and Whitening Activity of Bamboo Extracts
- Authors
- 송호선; 문효진; 박병언; 최방실; 이동자; 이지윤; 김창종; 심상수
- Issue Date
- 2007
- Publisher
- 대한약학회
- Keywords
- bamboo extracts; anti-oxidant; tyrosinase; melanin
- Citation
- 약 학 회 지, v.51, no.6, pp 500 - 507
- Pages
- 8
- Journal Title
- 약 학 회 지
- Volume
- 51
- Number
- 6
- Start Page
- 500
- End Page
- 507
- URI
- https://scholarworks.bwise.kr/cau/handle/2019.sw.cau/30827
- ISSN
- 0377-9556
- Abstract
- Phyllostachys nigravar. henonis), we measured DPPH assay, NBT/XO asay, intracelular ROS scavenging assay, tyrosinase asay and MSH-induced melanin production in B-16 cells. Bamboo extracts had dose-dependently anti-oxidant activity in DPPH, NBT/XOand intracellular ROS assay. Bamboo extracts appear to inhibit xanthine oxidase directly. Bamboo extracts inhibited not onlypurified tyrosinase activity but also inhibited tyrosinase activity and melanin production in B16 melanoma cells stimulatedby 1 M α-MSH. Anti-oxidant activity and cytotoxicity of ethyl acetate fraction was more potent than those of water fraction,whereas whitening effect of water fraction was stronger than ethyl acetate fraction. Therefore, these results suggest thatwater fraction of bamboo extracts may be useful for the development as whitening agents reducing cytotoxicity.Keywords . bamboo extracts, anti-oxidant, tyrosinase, melanin.... .. (Gramineae). ... ... .. , .. , ..
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