슬관절치환술 환자의 Cephalosporin계 항생제 사용에 대한 경제효율성 비교연구A Comparative Study of Use of Cephalosporins in Total Knee Replacement Surger in Terms of Economic Efficiency
- Authors
- 조동선; 송현주; 박성욱; 손의동
- Issue Date
- 2008
- Publisher
- 대한약학회
- Keywords
- antibiotics; cephalosporin; economic efficiency; TKR
- Citation
- 약 학 회 지, v.52, no.2, pp 101 - 110
- Pages
- 10
- Journal Title
- 약 학 회 지
- Volume
- 52
- Number
- 2
- Start Page
- 101
- End Page
- 110
- URI
- https://scholarworks.bwise.kr/cau/handle/2019.sw.cau/30954
- ISSN
- 0377-9556
- Abstract
- Total Knee Replacement (TKR) surgery is one of the invasive procedures for patients with late-stage knee
joint disorders. In the present study, economic efficiency was compared between uses of the 2nd and 3rd generation cephalosporins
for the prophylaxis before and after the surgery using frequency analysis in terms of various factors such as medication
costs, the number of days of antibiotic use and hospitalization due to TKR surgery. The results showed that the 3rd
generation cephalosporins did not reduce the infection rate and total medication costs, but rather raised antibiotic cost in
comparison with the 2nd ones. A frequent use of the 3rd ones is closely related to emergence of resistant bacterial strains.
Therefore, we suggest that unnecessary prescriptions for the broad spectrum antibiotics should be avoided.
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