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슬관절치환술 환자의 Cephalosporin계 항생제 사용에 대한 경제효율성 비교연구A Comparative Study of Use of Cephalosporins in Total Knee Replacement Surger in Terms of Economic Efficiency

Authors
조동선송현주박성욱손의동
Issue Date
2008
Publisher
대한약학회
Keywords
antibiotics; cephalosporin; economic efficiency; TKR
Citation
약 학 회 지, v.52, no.2, pp 101 - 110
Pages
10
Journal Title
약 학 회 지
Volume
52
Number
2
Start Page
101
End Page
110
URI
https://scholarworks.bwise.kr/cau/handle/2019.sw.cau/30954
ISSN
0377-9556
Abstract
Total Knee Replacement (TKR) surgery is one of the invasive procedures for patients with late-stage knee joint disorders. In the present study, economic efficiency was compared between uses of the 2nd and 3rd generation cephalosporins for the prophylaxis before and after the surgery using frequency analysis in terms of various factors such as medication costs, the number of days of antibiotic use and hospitalization due to TKR surgery. The results showed that the 3rd generation cephalosporins did not reduce the infection rate and total medication costs, but rather raised antibiotic cost in comparison with the 2nd ones. A frequent use of the 3rd ones is closely related to emergence of resistant bacterial strains. Therefore, we suggest that unnecessary prescriptions for the broad spectrum antibiotics should be avoided.
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