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Determination of silybin B in the different parts of silybum marianum using HPLC-UV

Authors
Rodriguez, J.P.Quilantang, N.G.Lee, J.S.Lee, J.M.Kim, H.Y.Shim, J.S.Lee, S.
Issue Date
2018
Publisher
Korean Society of Pharmacognosy
Keywords
HPLC-UV; Silybin B; Silybum marianum; Silymarin
Citation
Natural Product Sciences, v.24, no.2, pp 82 - 87
Pages
6
Journal Title
Natural Product Sciences
Volume
24
Number
2
Start Page
82
End Page
87
URI
https://scholarworks.bwise.kr/cau/handle/2019.sw.cau/3173
DOI
10.20307/nps.2018.24.2.82
ISSN
1226-3907
Abstract
Silymarin is the standardized extract from Silybum marianum which consists mainly of flavonoids and polyphenols. It is highly regarded for its hepatoprotective ability. Silybin B is a flavonolignan and one of the active components of silymarin. The content of silybin B in various parts of S. marianum was analyzed by HPLCUV. Results show that the extract of seeds contain the highest amount of silybin B (7.434 mg/g DW). The petioles of S. marianum showed a low content of silybin B. This study revealed that seeds of S. marianum contain high amount of silybin B and could be a good source of the compound. © 2018, Korean Society of Pharmacognosy. All rights reserved.
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