소아에서 발생한 Yersinia pseudotuberculosis 감염이 동반된 아급성 괴사성 림프절염 1례A Case of Subacute Necrotizing Lymphadenitis Associated with Yersinia Infection in a 12 Years Old Child
- Authors
- 심윤희; 임인석; 이동근
- Issue Date
- 2003
- Publisher
- 대한소아감염학회
- Keywords
- Kikuchi disease; Subacute necrotizing lymphadenitis; Y. pseudotuberculosis
- Citation
- Pediatric Infection and Vaccine, v.10, no.1, pp 123 - 126
- Pages
- 4
- Journal Title
- Pediatric Infection and Vaccine
- Volume
- 10
- Number
- 1
- Start Page
- 123
- End Page
- 126
- URI
- https://scholarworks.bwise.kr/cau/handle/2019.sw.cau/32229
- ISSN
- 2384-1079
2384-1087
- Abstract
- Kikuchi disease(subacute necrotizing lymphadenitis), first reported by Kikuchi and Fujimoto in 1972, is a benign self-limiting illness characterized by fever, neutropenia and cervical lymphadenopathy and develops predominantly in young women, especially in Asia. The cause of Kikuchi disease is unknown, but postinfectious(virus or bacteria) hyperimmune reaction has been suggested. Few pediatric cases have been reported. We experienced a case of Kikuchi disease associated with Yersinia pseudotuberculosis infection in 12-year-old girl. After she was admitted with cervical lymphadenopathy and headache, followed by sustained fever with leukopenia. All symptoms and signs did not seem to be responded to antimicobial treatment. Open biopsy of cervical lymph node was performed and showed findings consistent with subacute necrotizing lymphadenitis. Serologic studies were all negative except for Y. pseudotuberculosis. Fever subsided and lymphadenopathy improved after administration of oral steroid for 1 week.
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