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민속식물의 알도즈 환원효소 억제작용Aldose reductase inhibitory activity of the methanol extracts from Korean folk plants
- Issue Date
- 2012
- Publisher
- 충남대학교 농업과학연구소
- Keywords
- Aldose reductase inhibition; Cedrela sinensis; Diabetic complications; Folk plant
- Citation
- Korean Journal of Agricultural Science, v.39, no.2, pp 169 - 175
- Pages
- 7
- Journal Title
- Korean Journal of Agricultural Science
- Volume
- 39
- Number
- 2
- Start Page
- 169
- End Page
- 175
- ISSN
- 2466-2402
2466-2410
- Abstract
- To search for the aldose reductase (AR) inhibitors from Korean folk plants, the inhibition of rat lens AR in vitro using the methanol (MeOH) extracts from Korean folk plants was investigated. Among fifty four Korean folk plants tested, the MeOH extract of Cedrela sinensis showed highest inhibition of AR (IC50 value, 2.52 μg/ml). The plant C. sinensis has a possibility of new natural resources for the development of AR inhibitor for the prevention of diabetic complications.
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