Cluster analysis of incomplete microarray data with fuzzy clustering
- Authors
- 김대원
- Issue Date
- Jun-2007
- Publisher
- 한국지능시스템학회
- Keywords
- Bioinformatics; fuzzy clustering; Microarray; missing value
- Citation
- 한국지능시스템학회 논문지, v.17, no.3, pp 397 - 402
- Pages
- 6
- Journal Title
- 한국지능시스템학회 논문지
- Volume
- 17
- Number
- 3
- Start Page
- 397
- End Page
- 402
- URI
- https://scholarworks.bwise.kr/cau/handle/2019.sw.cau/35985
- ISSN
- 1976-9172
- Abstract
- In this paper, we present a method for clustering incomplete Microarray data using alternating optimization in which a prior imputation method is not required. To reduce the influence of imputation in preprocessing, we take an alternative optimization approach to find better estimates during iterative clustering process. This method improves the estimates of missing values by exploiting the cluster information such as cluster centroids and all available non-missing values in each iteration. The clustering results of the proposed method are more significantly relevant to the biological gene annotations than those of other methods, indicating its effectiveness and potential for clustering incomplete gene expression data.
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Collections - College of Software > School of Computer Science and Engineering > 1. Journal Articles
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