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Anti-oxidant activity of avicularin and isovitexin from Lespedeza cuneataopen access
- Authors
- Lee, Ju Sung; Lee, Ah Young; Quilantang, Norman G.; Geraldino, Paul John L.; Cho, Eun Ju; Lee, Sanghyun
- Issue Date
- Jun-2019
- Publisher
- 한국응용생명화학회
- Keywords
- Avicularin; High performance liquid chromatography; Isovitexin; Lespedeza cuneata; Radical scavenging activity
- Citation
- Journal of Applied Biological Chemistry, v.62, no.2, pp 143 - 147
- Pages
- 5
- Journal Title
- Journal of Applied Biological Chemistry
- Volume
- 62
- Number
- 2
- Start Page
- 143
- End Page
- 147
- ISSN
- 1976-0442
2234-7941
- Abstract
- This study evaluated the anti-oxidant activity of avicularin and isovitexin from Lespedeza cuneata using 2,2-diphenyl-1picrylhydrazyl (DPPH) and hydroxyl (OH) scavenging assays. The results showed that among the four fractions, the highest OH radical scavenging activity was exhibited by the n-butanol fraction. The DPPH radical scavenging activities of avicularin and isovitexin were higher than 50% at a concentration of 100 μg/mL. Moreover, one hundred micrograms per liter of avicularin and isovitexin exhibited effective anti-oxidant activity, with the OH radical scavenging rates being 87.54 and 91.48%, respectively. These results suggest that Lespedeza cuneata would be useful anti-oxidant agents from natural sources.
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