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Aldose reductase inhibition of the methanolic extracts of selected noxious and exotic plantsopen access

Authors
Lee, Ju SungWoo, Dong GeonCho, Ga EulLee, Sanghyun
Issue Date
Jun-2019
Publisher
한국응용생명화학회
Keywords
Aldose reductase; High-performance liquid chromatography; Noxious plant; Quercetin
Citation
Journal of Applied Biological Chemistry, v.62, no.2, pp 203 - 209
Pages
7
Journal Title
Journal of Applied Biological Chemistry
Volume
62
Number
2
Start Page
203
End Page
209
URI
https://scholarworks.bwise.kr/cau/handle/2019.sw.cau/36658
DOI
10.3839/jabc.2019.028
ISSN
1976-0442
2234-7941
Abstract
The inhibition of aldose reductase (AR) by the extracts from sixteen noxious and exotic plants was examined. Among them, Aster pilosus showed the highest inhibition of AR (IC50 value 0.11 μg/mL). This study showed that A. pilosus with promising AR-inhibitory activities can be utilized for the development of natural therapies for treating and managing diabetic complications.
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