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Preparation of UV-curable alginate derivatives for drug immobilization on dressing foam
- Authors
- Kim, Jae-Won; Kim, Eun-Hye; Han, Ga-Dug; Noh, Seung-Hyun; Pyun, Do-Gi; Ito, Yoshihiro; Nah, Jae-Woon; Lee, Jae-Gwan; Son, Tae-Il
- Issue Date
- Oct-2017
- Publisher
- ELSEVIER SCIENCE INC
- Keywords
- Az-alginate; Biocompatible; Dressing foam; Drug immobilization; Photo-curing
- Citation
- JOURNAL OF INDUSTRIAL AND ENGINEERING CHEMISTRY, v.54, pp 350 - 358
- Pages
- 9
- Journal Title
- JOURNAL OF INDUSTRIAL AND ENGINEERING CHEMISTRY
- Volume
- 54
- Start Page
- 350
- End Page
- 358
- ISSN
- 1226-086X
1876-794X
- Abstract
- The purpose of this study was to develop dressing foam with drug immobilization abilities by using Azidophenyl alginate (Az-alginate). We characterized prepared Az-alginate. Through the patterning test, immobilization of drug was confirmed. Degrees of photo-curing were identified by the photo-curing ratio test. Cytotoxicity test confirmed that Az-alginate was biocompatible. The protein releasing test measured the degree of drug released according to the concentration of Az-alginate. By examination of the water absorbency and moisture vapor transmission rate, characteristics of the dressing foam with photo-cured Az-alginate were measured. From the results of these tests, Az-alginate can be applied to the dressing foam. (C) 2017 The Korean Society of Industrial and Engineering Chemistry. Published by Elsevier B.V. All rights reserved.
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