Far-infrared Ray-mediated Antioxidant Potentials are Important for Attenuating Psychotoxic Disorders
- Authors
- Sharma, Naveen; Shin, Eun-Joo; Kim, Nam Hun; Cho, Eun-Hee; Bao Trong Nguyen; Jeong, Ji Hoon; Jang, Choon Gon; Nah, Seung-Yeol; Kim, Hyoung-Chun
- Issue Date
- 2019
- Publisher
- BENTHAM SCIENCE PUBL LTD
- Keywords
- Far-infrared ray; nuclear factor E2-related factor 2; glutathione peroxidase-1; JAK2/STAT3; M1 mAChR; dopamine D1 receptor; protein kinase C delta gene; neuropsychotoxic conditions
- Citation
- CURRENT NEUROPHARMACOLOGY, v.17, no.10, pp 990 - 1002
- Pages
- 13
- Journal Title
- CURRENT NEUROPHARMACOLOGY
- Volume
- 17
- Number
- 10
- Start Page
- 990
- End Page
- 1002
- URI
- https://scholarworks.bwise.kr/cau/handle/2019.sw.cau/38886
- DOI
- 10.2174/1570159X17666190228114318
- ISSN
- 1570-159X
1875-6190
- Abstract
- Far-infrared ray (FIR) is an electromagnetic wave that produces various health benefits against pathophysiological conditions, such as diabetes mellitus, renocardiovascular disorders, stress, and depression etc. However, the therapeutic application on the FIR-mediated protective potentials remains to be further extended. To achieve better understanding on FIR-mediated therapeutic potentials, we summarized additional fmdings in the present study that exposure to FIR ameliorates stressful condition, memory impairments, drug dependence, and mitochondrial dysfunction in the central nervous system. In this review, we underlined that FIR requires modulations of janus kinase 2 / signal transducer and activator of transcription 3 (JAK2/STAT3), nuclear factor E2-related factor 2 (Nrf-2), muscarinic M1 acetylcholine receptor (M1 mAChR), dopamine D1 receptor, protein kinase C delta gene, and glutathione peroxidase-1 gene for exerting the protective potentials in response to neuropsychotoxic conditions.
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