Comparison of Electroencephalography (EEG) Coherence between Major Depressive Disorder (MDD) without Comorbidity and MDD Comorbid with Internet Gaming Disorderopen access
- Authors
- Youh, Joohyung; Hong, Ji Sun; Han, Doug Hyun; Chung, Un Sun; Min, Kyoung Joon; Lee, Young Sik; Kim, Sun Mi
- Issue Date
- Jul-2017
- Publisher
- KOREAN ACAD MEDICAL SCIENCES
- Keywords
- Internet Gaming Disorder; Major Depressive Disorder; Quantitative Electroencephalogram; Coherence
- Citation
- JOURNAL OF KOREAN MEDICAL SCIENCE, v.32, no.7, pp 1160 - 1165
- Pages
- 6
- Journal Title
- JOURNAL OF KOREAN MEDICAL SCIENCE
- Volume
- 32
- Number
- 7
- Start Page
- 1160
- End Page
- 1165
- URI
- https://scholarworks.bwise.kr/cau/handle/2019.sw.cau/4274
- DOI
- 10.3346/jkms.2017.32.7.1160
- ISSN
- 1011-8934
1598-6357
- Abstract
- Internet gaming disorder (IGD) has many comorbid psychiatric problems including major depressive disorder (MDD). In the present study, we compared the neurobiological differences between MDD without comorbidity (MDD-only) and MDD comorbid with IGD (MDD+IGD) by analyzing the quantitative electroencephalogram (QEEG) findings. We recruited 14 male MDD+IGD (mean age, 20.0 +/- 5.9 years) and 15 male MDD-only (mean age, 20.3 +/- 5.5 years) patients. The electroencephalography (EEG) coherences were measured using a 21-channel digital EEG system and computed to assess synchrony in the frequency ranges of alpha (7.5-12.5 Hz) and beta (12.5-35.0 Hz) between the following 12 electrode site pairs: inter-hemispheric (Fp1-Fp2, F7-F8, T3-T4, and P3-P4) and intra-hemispheric (F7-T3, F8-T4, C3-P3, C4-P4, T5-O1, T6-O2, P3-O1, and P4-O2) pairs. Differences in inter-and intra-hemispheric coherence values for the frequency bands between groups were analyzed using the independent t-test. Inter-hemispheric coherence value for the alpha band between Fp1-Fp2 electrodes was significantly lower in MDD+IGD than MDD-only patients. Intra-hemispheric coherence value for the alpha band between P3-O1 electrodes was higher in MDD+ IGD than MDD-only patients. Intra-hemispheric coherence values for the beta band between F8-T4, T6-O2, and P4-O2 electrodes were higher in MDD+ IGD than MDD-only patients. There appears to be an association between decreased inter-hemispheric connectivity in the frontal region and vulnerability to attention problems in the MDD+ IGD group. Increased intra-hemisphere connectivity in the fronto-temporo-parieto-occipital areas may result from excessive online gaming.
- Files in This Item
-
- Appears in
Collections - College of Medicine > College of Medicine > 1. Journal Articles
![qrcode](https://api.qrserver.com/v1/create-qr-code/?size=55x55&data=https://scholarworks.bwise.kr/cau/handle/2019.sw.cau/4274)
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.