Detailed Information
Cited 0 time in 
Cited 0 time in 
Cited 0 time in
Metadata Downloads
Visible Light-Promoted Friedel-Crafts-Type Chloroacylation of Alkenes to β-Chloroketones
- Authors
- Patil D.V.; Kim H.Y.; Oh K.
- Issue Date
- 17-Apr-2020
- Publisher
- American Chemical Society
- Citation
- Organic Letters, v.22, no.8, pp 3018 - 3022
- Pages
- 5
- Journal Title
- Organic Letters
- Volume
- 22
- Number
- 8
- Start Page
- 3018
- End Page
- 3022
- ISSN
- 1523-7060
1523-7052
- Abstract
- The photoredox chloroacylation of alkenes has been developed as a substitute for the Friedel-Crafts acylation of alkenes to β-chloroketones. The direct generation of acyl radical species from acid chlorides under the photoredox conditions allows the formation of β-chloroketones without dehydrochlorination with the help of KHCO3. The synthetic utility of the current method is demonstrated in the one-pot synthesis of dihydroisoxazole, dihydropyrazole, and dihydropyrimidine-2-thione in 1 mmol scale. © 2020 American Chemical Society.
- Files in This Item
- There are no files associated with this item.
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.