Recent advances in sensitive surface-enhanced Raman scattering-based lateral flow assay platforms for point-of-care diagnostics of infectious diseases
- Authors
- Kim, Kihyun; Kashefi-Kheyrabadi, Leila; Joung, Younju; Kim, Kyeongnyeon; Dang, Hajun; Chavan, Sachin Ganpat; Lee, Min-Ho; Choo, Jaebum
- Issue Date
- 15-Feb-2021
- Publisher
- Elsevier B.V.
- Keywords
- In vitro diagnostics (IVD); Infectious disease; Lateral flow assay (LFA); Point-of-care (POC); SARS-CoV-2; Surface-enhanced Raman scattering (SERS)
- Citation
- Sensors and Actuators, B: Chemical, v.329
- Journal Title
- Sensors and Actuators, B: Chemical
- Volume
- 329
- URI
- https://scholarworks.bwise.kr/cau/handle/2019.sw.cau/44126
- DOI
- 10.1016/j.snb.2020.129214
- ISSN
- 0925-4005
0925-4005
- Abstract
- This review reports the recent advances in surface-enhanced Raman scattering (SERS)-based lateral flow assay (LFA) platforms for the diagnosis of infectious diseases. As observed through the recent infection outbreaks of COVID-19 worldwide, a timely diagnosis of the disease is critical for preventing the spread of a disease and to ensure epidemic preparedness. In this regard, an innovative point-of-care diagnostic method is essential. Recently, SERS-based assay platforms have received increasing attention in medical communities owing to their high sensitivity and multiplex detection capability. In contrast, LFAs provide a user-friendly and easily accessible sensing platform. Thus, the combination of LFAs with a SERS detection system provides a new diagnostic modality for accurate and rapid diagnoses of infectious diseases. In this context, we briefly discuss the recent application of LFA platforms for the POC diagnosis of SARS-CoV-2. Thereafter, we focus on the recent advances in SERS-based LFA platforms for the early diagnosis of infectious diseases and their applicability for the rapid diagnosis of SARS-CoV-2. Finally, the key issues that need to be addressed to accelerate the clinical translation of SERS-based LFA platforms from the research laboratory to the bedside are discussed. © 2020 Elsevier B.V.
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Collections - College of Natural Sciences > Department of Chemistry > 1. Journal Articles
- College of ICT Engineering > School of Integrative Engineering > 1. Journal Articles
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