Usefulness of preoperative breast magnetic resonance imaging with a dedicated axillary sequence for the detection of axillary lymph node metastasis in patients with early ductal breast cancer
- Authors
- Ahn, H.S.; Jang, M.; Kim, S.M.; La Yun, B.; Lee, S.H.
- Issue Date
- Dec-2019
- Publisher
- Springer-Verlag Italia s.r.l.
- Keywords
- Axilla; Breast cancer; Lymph node; Magnetic resonance imaging; Metastasis
- Citation
- Radiologia Medica, v.124, no.12, pp 1220 - 1228
- Pages
- 9
- Journal Title
- Radiologia Medica
- Volume
- 124
- Number
- 12
- Start Page
- 1220
- End Page
- 1228
- URI
- https://scholarworks.bwise.kr/cau/handle/2019.sw.cau/44567
- DOI
- 10.1007/s11547-019-01072-2
- ISSN
- 0033-8362
1826-6983
- Abstract
- Objective: Axillary staging of primary breast cancer is important; however, axillary staging using advanced magnetic resonance imaging (MRI) techniques is very difficult to use. Therefore, we want to evaluate the diagnostic performance of preoperative MRI with a dedicated axillary sequence for axillary lymph node (ALN) metastasis in patients with early ductal breast cancer and determine potential predictors of axillary nodal positivity. Materials and methods: We retrospectively reviewed the MRI findings for 74 consecutive patients diagnosed with invasive breast cancer. The diagnostic performances of axial images alone and axial + reconstructed coronal images for the detection of ALN metastasis were evaluated. The clinicopathological and MRI features of the primary breast cancer lesions were determined. Results: The sensitivity (52.9% vs. 47.1%), specificity (89.5% vs. 71.9%), positive predictive value (60% vs. 33.3%), and negative predictive value (86.4% vs. 82%) for the preoperative detection of ALN metastasis were higher for axial + coronal images than for axial images. In addition, the area under the receiver operating characteristic curve value was higher for axial + coronal images than for axial images (0.595 vs. 0.712, p = 0.043). Peritumoral high signal intensity on T2-weighted images (p = 0.015) of the primary tumor was significantly associated with ALN metastasis. Conclusion: Our findings suggest that preoperative axial + reconstructed coronal MR images exhibit good diagnostic performance for ALN metastasis in patients with early ductal breast cancer. In addition, peritumoral high signal intensity on T2-weighted images of the primary tumor can be used as a predictor of ALN metastasis in these patients. © 2019, Italian Society of Medical Radiology.
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