Validation of web-based thyroid imaging reporting and data system in atypia or follicular lesion of undetermined significance thyroid nodules
- Authors
- Ha, S.M.; Na, D.G.; Kim, J.-H.; Kim, S.C.; Baek, J.H.
- Issue Date
- Jul-2019
- Publisher
- John Wiley and Sons Inc.
- Keywords
- AUS/FLUS; thyroid cancer; thyroid nodule; ultrasound
- Citation
- Head and Neck, v.41, no.7, pp 2215 - 2224
- Pages
- 10
- Journal Title
- Head and Neck
- Volume
- 41
- Number
- 7
- Start Page
- 2215
- End Page
- 2224
- URI
- https://scholarworks.bwise.kr/cau/handle/2019.sw.cau/44767
- DOI
- 10.1002/hed.25677
- ISSN
- 1043-3074
1097-0347
- Abstract
- Background: Atypia of undetermined significance/follicular lesion of undetermined significance (AUS/FLUS) show variable malignancy risk. We validated the web-based predictive models and the scoring system by the American College of Radiology (ACR) for AUS/FLUS nodules to stratify the malignancy risk. Methods: From January 2011 to November 2014, 275 consecutive nodules diagnosed as AUS/FLUS were enrolled. The discrimination and calibration ability of a web-based scoring with inclusion of biopsy result and sonographic features, old web-based scoring model without biopsy result, and ACR models were assessed. Results: The areas under the receiver operating characteristic curve of the validation set were 0.670 for the new web-based model, 0.710 for the old web-based model, and 0.732 for the ACR scoring risk-stratification model. All models were well calibrated. Conclusion: The web-based scoring risk-stratification model using the combined information of ultrasonography features and biopsy result for AUS/FLUS nodules to stratify malignancy risk presents an acceptable predictive accuracy. © 2019 Wiley Periodicals, Inc.
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