Langerhans cell histiocytosis that improved with oral isotretinoin therapy
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Choi, J.H. | - |
dc.contributor.author | Shim, H.C. | - |
dc.contributor.author | Kim, J.H. | - |
dc.contributor.author | Kim, J.B. | - |
dc.contributor.author | Shin, M.S. | - |
dc.contributor.author | Park, H. | - |
dc.contributor.author | Lee, J.S. | - |
dc.contributor.author | Jo, O.J. | - |
dc.contributor.author | Song, K.Y. | - |
dc.date.accessioned | 2021-06-18T12:44:23Z | - |
dc.date.available | 2021-06-18T12:44:23Z | - |
dc.date.issued | 2010-10 | - |
dc.identifier.issn | 0494-4739 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/cau/handle/2019.sw.cau/46899 | - |
dc.description.abstract | Langerhans cell histiocytosis (LCH) is a reactive disease in which abnormal Langerhans cells accumulate in various body sites. We report here on a 51-year-old male patient with LCH that was classified as single-system disease (restricted LCH). The skin lesions were a small, deep ulcer in the right inguinal area and multiple erythematous papules scattered on the lower abdomen, and the patient had these lesions for 1 year. The histopathologic examination revealed a dense histiocytic infiltration in the dermis, and most of the cells showed the characteristics of LCH cells. The immunohistochemistry for S-100 protein and CD1a complex all showed positive results. The patient was much improved after surgical excision of the inguinal ulcer and administering oral isotretinoin (20 mg daily) for 8 months, and there was no recurrence. We think retinoid is an effective treatment option for LCH, especially for single system disease. | - |
dc.format.extent | 5 | - |
dc.language | 한국어 | - |
dc.language.iso | KOR | - |
dc.publisher | 대한피부과학회 | - |
dc.title | Langerhans cell histiocytosis that improved with oral isotretinoin therapy | - |
dc.title.alternative | Langerhans Cell Histiocytosis That Improved with Oral Isotretinoin Therapy | - |
dc.type | Article | - |
dc.identifier.bibliographicCitation | Korean Journal of Dermatology, v.48, no.10, pp 893 - 897 | - |
dc.identifier.kciid | ART001493988 | - |
dc.description.isOpenAccess | N | - |
dc.identifier.scopusid | 2-s2.0-79960897458 | - |
dc.citation.endPage | 897 | - |
dc.citation.number | 10 | - |
dc.citation.startPage | 893 | - |
dc.citation.title | Korean Journal of Dermatology | - |
dc.citation.volume | 48 | - |
dc.type.docType | Article | - |
dc.publisher.location | 대한민국 | - |
dc.subject.keywordAuthor | Isotretinoin | - |
dc.subject.keywordAuthor | Langerhans cell histiocytosis | - |
dc.description.journalRegisteredClass | scopus | - |
dc.description.journalRegisteredClass | kci | - |
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