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Colorimetric detection of mercuric ion (Hg2+) in aqueous media using DNA-functionalized gold nanoparticles
- Authors
- Lee, J.-S.; Han, M.S.; Mirkin, C.A.
- Issue Date
- 2007
- Keywords
- Colorimetric detection; DNA; Mercury; Nanoparticles; Sensors
- Citation
- Angewandte Chemie - International Edition, v.46, no.22, pp 4093 - 4096
- Pages
- 4
- Journal Title
- Angewandte Chemie - International Edition
- Volume
- 46
- Number
- 22
- Start Page
- 4093
- End Page
- 4096
- ISSN
- 1433-7851
1521-3773
- Abstract
- Color is everything: Hg2+ in aqueous media is detected by the formation of thymidine-Hg2+-thymidine coordination complexes, which raises the melting temperature of the DNA-hybridized gold nanoparticle probes and thus the temperature at which the probes disperse and effect a purple-to-red color change. The method has very high sensitivity and selectivity, and it provides a simple and fast colorimetric readout (see picture). (Figure Presented) © 2007 Wiley-VCH Verlag GmbH & Co. KGaA.
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