A case of neuroblastoma-like schwannoma

Abstract

Schwannoma (neurilemmoma) is a common, benign, nerve-sheath tumor, and has classically been described as having a biphasic histologic appearance with alternating areas of cellular (Antoni A) and loose myxoid (Antoni B) tissues. Neuroblastom-like schwannoma is an extremely rare variant, which shows giant rosette-mimicking neuroblastoma. It must be differentiated from neuroblastoma, hyalizing spindle-cell tumors with giant rosettes, peripheral primitive neuroectodermal tumors, dendritic cell neurofibroma with pseudorosette, and malignant changes of schwannoma. To the best of our knowledge, there have been no reports of neuroblastoma-like schwannoma in Korea. We herein report a case of neuroblastoma-like schwannoma, along with a review of pertinent literature.