Fabrication of All Glass Bifurcation Microfluidic Chip for Blood Plasma Separation
- Authors
- Jang, Hyungjun; Haq, Muhammad Refatul; Ju, Jonghyun; Kim, Youngkyu; Kim, Seok-min; Lim, Jiseok
- Issue Date
- Mar-2017
- Publisher
- MDPI AG
- Keywords
- glass molding; amorphous carbon mold; microfluidics; blood plasma separation; bifurcation microfluidic chip
- Citation
- MICROMACHINES, v.8, no.3
- Journal Title
- MICROMACHINES
- Volume
- 8
- Number
- 3
- URI
- https://scholarworks.bwise.kr/cau/handle/2019.sw.cau/4757
- DOI
- 10.3390/mi8030067
- ISSN
- 2072-666X
- Abstract
- An all-glass bifurcation microfluidic chip for blood plasma separation was fabricated by a cost-effective glass molding process using an amorphous carbon (AC) mold, which in turn was fabricated by the carbonization of a replicated furan precursor. To compensate for the shrinkage during AC mold fabrication, an enlarged photoresist pattern master was designed, and an AC mold with a dimensional error of 2.9% was achieved; the dimensional error of the master pattern was 1.6%. In the glass molding process, a glass microchannel plate with negligible shape errors (similar to 1.5%) compared to AC mold was replicated. Finally, an all-glass bifurcation microfluidic chip was realized by micro drilling and thermal fusion bonding processes. A separation efficiency of 74% was obtained using the fabricated all-glass bifurcation microfluidic chip.
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Collections - College of Engineering > School of Mechanical Engineering > 1. Journal Articles
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