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Editorial Commentary: Stem Cell Therapy for the Knee: Heterogeneity in Cell Sources, Delivery Methods, and Concomitant Surgery Needs to Be Considered

Authors
Park, Y.-B.
Issue Date
Jan-2021
Publisher
W.B. Saunders
Citation
Arthroscopy - Journal of Arthroscopic and Related Surgery, v.37, no.1, pp 379 - 380
Pages
2
Journal Title
Arthroscopy - Journal of Arthroscopic and Related Surgery
Volume
37
Number
1
Start Page
379
End Page
380
URI
https://scholarworks.bwise.kr/cau/handle/2019.sw.cau/47888
DOI
10.1016/j.arthro.2020.07.035
ISSN
0749-8063
1526-3231
Abstract
Mesenchymal stem cells (MSCs) have been investigated for the treatment of knee osteoarthritis because of their unique properties, including self-renewal, multi-linear cellular differentiation, and immunomodulatory capacity. However, the efficacy of MSCs for positive clinical outcomes in the treatment of knee osteoarthritis remains controversial. Because clinical studies in general have high variability, the heterogeneity in the sources of the stem cells used, efficacy of delivery methods, and concomitant surgery should be carefully considered to interpret the benefits of MSC therapy for knee osteoarthritis. © 2020 Arthroscopy Association of North America
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의과대학 (의학부(임상-광명))
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