분자영상을 위한 다기능성 나노입자Multifunctional Nanoparticles for Molecular Imaging
- Authors
- Kang, Eunah; Kim, Kwangmeyung; Kwon, Ick Chan
- Issue Date
- Feb-2009
- Publisher
- KOREAN MEDICAL ASSOC
- Keywords
- Bioimaging; Multimodality; Nanoparticles; Activatable; Targeting; Biodistribution; 바이오이미징; 나노입자; 활성화; 표적; 생체분포; 다중영상
- Citation
- JOURNAL OF THE KOREAN MEDICAL ASSOCIATION, v.52, no.2, pp 125 - 134
- Pages
- 10
- Journal Title
- JOURNAL OF THE KOREAN MEDICAL ASSOCIATION
- Volume
- 52
- Number
- 2
- Start Page
- 125
- End Page
- 134
- URI
- https://scholarworks.bwise.kr/cau/handle/2019.sw.cau/48024
- DOI
- 10.5124/jkma.2009.52.2.125
- ISSN
- 1975-8456
2093-5951
- Abstract
- Molecular imaging is a bioimaging that can detect biochemically and genetically relevant events in molecular level in cells and tissues via quantitative imaging signal. Molecular imaging provides potential advantages to examine early diagnosis of specific diseases, to screen new candidates of a drug, to monitor therapeutic effects in real time, and to communicate with both diagnosis and therapeutics. These diverse advantages of molecular imaging can be allowed by development of nanoplatform technology. The nanoplatform-based probes for molecular imaging is widely investigated to grant multimodal molecular imaging and drug delivery together with medical imagings, which includes the issues of biocompatibility, targeting moiety, protease-specific peptide substrate, quenching/dequenching system etc. In this paper, nanoplatform-based probes are reviewed in aspects of cancer targeting for diagnosis and therapy and multimodal molecular imaging with inorganic/organic hybrid nanoparticles.
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Collections - College of Engineering > School of Chemical Engineering and Material Science > 1. Journal Articles
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