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Determination of silymarin and silybin diastereomers in korean milk thistle using hplc/uv analysisHPLC 분석을 통한 한국산 밀크씨슬 중 실리마린과 실리빈의 정량
- Authors
- Kim, J.; Paje, L.A.; Choi, J.W.; Lee, H.-D.; Shim, J.S.; Shim, J.; Geraldino, P.J.L.; Lee, S.
- Issue Date
- 2020
- Publisher
- Korean Society of Pharmacognosy
- Keywords
- HPLC; Silybin diastereomer; Silybum marianum; Silymarin
- Citation
- Korean Journal of Pharmacognosy, v.51, no.4, pp 297 - 301
- Pages
- 5
- Journal Title
- Korean Journal of Pharmacognosy
- Volume
- 51
- Number
- 4
- Start Page
- 297
- End Page
- 301
- ISSN
- 0253-3073
- Abstract
- Silymarin (SM) and silybin diastereomers (SD) in milk thistle (Silybum marianum) were determined using highperformance liquid chromatography and quantified using a reverse-phase column in a gradient elution system. UV detection was performed at 288 nm. The content of SM and SD in milk thistle was 3.236 and 0.553 mg/g DW, respectively. Determining the presence and quantifying the content of SM and SD in milk thistle are vital for the pharmaceutical industry to identify optimal sources for developing health supplements or therapeutics. © 2020, Korean Society of Pharmacognosy. All rights reserved.
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