Effect of plant-based compounds on the antifungal and antiaflatoxigenic efficiency of strobilurins against Aspergillus flavus
DC Field | Value | Language |
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dc.contributor.author | Tian, F. | - |
dc.contributor.author | Lee, S.Y. | - |
dc.contributor.author | Woo, S.Y. | - |
dc.contributor.author | Choi, H.Y. | - |
dc.contributor.author | Park, S.B. | - |
dc.contributor.author | Chun, Hyang Sook | - |
dc.date.accessioned | 2021-08-27T06:40:19Z | - |
dc.date.available | 2021-08-27T06:40:19Z | - |
dc.date.issued | 2021-08-05 | - |
dc.identifier.issn | 0304-3894 | - |
dc.identifier.issn | 1873-3336 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/cau/handle/2019.sw.cau/48931 | - |
dc.description.abstract | Aflatoxins are a group of carcinogenic and mutagenic fungal secondary metabolites that have threatened human health and global food security. Aflatoxin contamination can be controlled by applying fungicides, such as strobilurins. Although these compounds have been effective, they may be risky to the environment due to their wide usage. In this study, plant-based compounds were tested to promote the performance of strobilurins (azoxystrobin, pyraclostrobin) against aflatoxigenic Aspergillus flavus; six natural compounds, namely baicalein, nobiletin, meso-dihydroguaiaretic acid, pinoresinol, syringaresinol, and celastrol, were found to exhibit synergistic antifungal effects with strobilurins with fractional inhibitory concentration index < 0.5. Among them, baicalein showed no inhibitory effects on A. flavus when applied alone, but strongly enhanced the in vitro and in situ antifungal and antiaflatoxigenic efficacy of strobilurins and transformed them from fungistatic to fungicidal agents. Therefore, baicalein may be used as an effective natural chemosensitizing agent to improve the performance of strobilurins against A. flavus. The findings of this study provide novel insights for the development of safer and more effective strategies for the control of aflatoxin contamination. © 2021 Elsevier B.V. | - |
dc.language | 영어 | - |
dc.language.iso | ENG | - |
dc.publisher | Elsevier B.V. | - |
dc.title | Effect of plant-based compounds on the antifungal and antiaflatoxigenic efficiency of strobilurins against Aspergillus flavus | - |
dc.type | Article | - |
dc.identifier.doi | 10.1016/j.jhazmat.2021.125663 | - |
dc.identifier.bibliographicCitation | Journal of Hazardous Materials, v.415 | - |
dc.description.isOpenAccess | N | - |
dc.identifier.wosid | 000659042200002 | - |
dc.identifier.scopusid | 2-s2.0-85102892951 | - |
dc.citation.title | Journal of Hazardous Materials | - |
dc.citation.volume | 415 | - |
dc.type.docType | Article | - |
dc.publisher.location | 네델란드 | - |
dc.subject.keywordAuthor | Aflatoxin | - |
dc.subject.keywordAuthor | Baicalein | - |
dc.subject.keywordAuthor | Fungicide | - |
dc.subject.keywordAuthor | Secondary metabolite | - |
dc.subject.keywordAuthor | Synergistic effect | - |
dc.subject.keywordPlus | Aspergillus | - |
dc.subject.keywordPlus | Food supply | - |
dc.subject.keywordPlus | Fungicides | - |
dc.subject.keywordPlus | Metabolites | - |
dc.subject.keywordPlus | Antifungals | - |
dc.subject.keywordPlus | Aspergillus flavus | - |
dc.subject.keywordPlus | Baicalein | - |
dc.subject.keywordPlus | Carcinogenics | - |
dc.subject.keywordPlus | Global food security | - |
dc.subject.keywordPlus | Human health | - |
dc.subject.keywordPlus | Performance | - |
dc.subject.keywordPlus | Secondary metabolites | - |
dc.subject.keywordPlus | Strobilurins | - |
dc.subject.keywordPlus | Synergistic effect | - |
dc.subject.keywordPlus | Aflatoxins | - |
dc.subject.keywordPlus | bacterium | - |
dc.subject.keywordPlus | concentration (composition) | - |
dc.subject.keywordPlus | food security | - |
dc.subject.keywordPlus | in situ measurement | - |
dc.subject.keywordPlus | inhibitor | - |
dc.subject.keywordPlus | performance assessment | - |
dc.subject.keywordPlus | secondary metabolite | - |
dc.subject.keywordPlus | Aspergillus flavus | - |
dc.relation.journalResearchArea | Engineering | - |
dc.relation.journalResearchArea | Environmental Sciences & Ecology | - |
dc.relation.journalWebOfScienceCategory | Engineering, Environmental | - |
dc.relation.journalWebOfScienceCategory | Environmental Sciences | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
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