Clinical Characteristics of Allergy to a Brinzolamide 1.0%/Brimonidine 0.2% Fixed Combination in Korean Glaucoma Patients
- Authors
- Park, In Ki; Bae, Seon Ha; Kim, Kyoung Woo; Chun, Yeoun Sook
- Issue Date
- Sep-2020
- Publisher
- KOREAN OPHTHALMOLOGICAL SOC
- Keywords
- Allergy; Brinzolamide 1.0%/Brimonidine 0.2% Fixed Combination (BBFC); Glaucoma
- Citation
- JOURNAL OF THE KOREAN OPHTHALMOLOGICAL SOCIETY, v.61, no.9, pp 1065 - 1071
- Pages
- 7
- Journal Title
- JOURNAL OF THE KOREAN OPHTHALMOLOGICAL SOCIETY
- Volume
- 61
- Number
- 9
- Start Page
- 1065
- End Page
- 1071
- URI
- https://scholarworks.bwise.kr/cau/handle/2019.sw.cau/52025
- DOI
- 10.3341/jkos.2020.61.9.1065
- ISSN
- 0378-6471
2092-9374
- Abstract
- Purpose: We describe the clinical aspects of allergy to a brinzolamide 1.0%/brimonidine 0.2% fixed combination (BBFC) in Korean patients with glaucoma. Methods: The medical records of 117 glaucoma patients treated with BBFC were retrospectively analyzed in terms of sex, age, glaucoma type, follow-up period after prescription of eyedrops, number of eyedrop preparations used, allergy onset, and clinical characteristics. Results: The incidence of ocular allergy during BBFC use was 12.8%. Allergy developed after an average of 8.58 months (range, 0.93-25.80 months); half of all allergies were evident within the first 5 months. The most common type of allergy was follicular conjunctivitis (53.4%), followed by papillary conjunctivitis and blepharoconjunctivitis. Systemic side-effects and eye discomfort (0.09%) were largely confined to non-allergic patients. Conclusions: An understanding of the clinical pattern of BBFC allergy in Korean glaucoma patients could facilitate treatment compliance and patients' education.
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