Genetic association of polymorphisms in porcine RGS16 with porcine circovirus viral load in naturally infected Yorkshire pigs
DC Field | Value | Language |
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dc.contributor.author | Lee, Seung-Hoon | - |
dc.contributor.author | Lim, Kyu-Sang | - |
dc.contributor.author | Hong, Ki-Chang | - |
dc.contributor.author | Kim, Jun-Mo | - |
dc.date.accessioned | 2021-12-10T08:40:43Z | - |
dc.date.available | 2021-12-10T08:40:43Z | - |
dc.date.issued | 2021 | - |
dc.identifier.issn | 2672-0191 | - |
dc.identifier.issn | 2055-0391 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/cau/handle/2019.sw.cau/52435 | - |
dc.description.abstract | Regulator of G protein signaling 16 (RGS16) is known to be associated with porcine circovirus type 2 (PCV2). PCV2 associated disease (PCVAD) is a serious problem in the swine industry. The representative symptoms of PCVAD are high viral titer proliferation and decreased average daily gain. In this study, we identified single nucleotide polymorphisms (SNPs) in the RGS16 region, including the upstream region. Of the 22 identified SNPs, rs332913874, rs326071195, and rs318298586 were genotyped in 142 Yorkshire pigs. These SNPs were significantly associated with the PCV2 viral load. Moreover, the haplotype combination was also related to the PCV2 viral load. The haplotype and diplotype analysis also had a significant difference with the PCV2 viral load. Taken together, our results suggest that RGS16 SNPs considerably affect the PCV2 viral load. | - |
dc.format.extent | 9 | - |
dc.language | 영어 | - |
dc.language.iso | ENG | - |
dc.publisher | 한국축산학회 | - |
dc.title | Genetic association of polymorphisms in porcine RGS16 with porcine circovirus viral load in naturally infected Yorkshire pigs | - |
dc.type | Article | - |
dc.identifier.doi | 10.5187/jast.2021.e105 | - |
dc.identifier.bibliographicCitation | 한국축산학회지, v.63, no.6, pp 1223 - 1231 | - |
dc.identifier.kciid | ART002780907 | - |
dc.description.isOpenAccess | Y | - |
dc.identifier.wosid | 000733814000002 | - |
dc.identifier.scopusid | 2-s2.0-85122561075 | - |
dc.citation.endPage | 1231 | - |
dc.citation.number | 6 | - |
dc.citation.startPage | 1223 | - |
dc.citation.title | 한국축산학회지 | - |
dc.citation.volume | 63 | - |
dc.publisher.location | 영국 | - |
dc.subject.keywordAuthor | PCV2 | - |
dc.subject.keywordAuthor | Viral load | - |
dc.subject.keywordAuthor | RGS16 | - |
dc.subject.keywordAuthor | Single nucleotide polymorphism | - |
dc.subject.keywordAuthor | Pig | - |
dc.subject.keywordPlus | MULTISYSTEMIC WASTING SYNDROME | - |
dc.subject.keywordPlus | PROTEIN SIGNALING 16 | - |
dc.subject.keywordPlus | TYPE-2 PCV2 | - |
dc.subject.keywordPlus | ORF3 PROTEIN | - |
dc.subject.keywordPlus | REGULATOR | - |
dc.subject.keywordPlus | EXPRESSION | - |
dc.subject.keywordPlus | ANTIBODIES | - |
dc.subject.keywordPlus | CELLS | - |
dc.subject.keywordPlus | DNA | - |
dc.relation.journalResearchArea | Agriculture | - |
dc.relation.journalResearchArea | Biotechnology & Applied Microbiology | - |
dc.relation.journalResearchArea | Veterinary Sciences | - |
dc.relation.journalWebOfScienceCategory | Agriculture, Dairy & Animal Science | - |
dc.relation.journalWebOfScienceCategory | Biotechnology & Applied Microbiology | - |
dc.relation.journalWebOfScienceCategory | Veterinary Sciences | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.description.journalRegisteredClass | kci | - |
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