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Synthesis of SPIO-chitosan microspheres for MRI-detectable embolotherapy
- Authors
- Lee, H.S.; Kim, E.H.; Shao, H.P.; Kwak, B.K.
- Issue Date
- May-2005
- Publisher
- ELSEVIER SCIENCE BV
- Keywords
- superparamagnetic iron oxide; sonochemical method; ferrofluid; MRI; embolic material; chitosan; microspheres; rabbit; kidney
- Citation
- JOURNAL OF MAGNETISM AND MAGNETIC MATERIALS, v.293, no.1, pp 102 - 105
- Pages
- 4
- Journal Title
- JOURNAL OF MAGNETISM AND MAGNETIC MATERIALS
- Volume
- 293
- Number
- 1
- Start Page
- 102
- End Page
- 105
- ISSN
- 0304-8853
1873-4766
- Abstract
- Spherical SPIO nanoparticles were synthesized and embedded in polyglucosamine (chitosan) by a sonochemical method. The embedded microspheres were shifted out in the range of 100-150 mu m. The microspheres were injected into the kidney of a New Zealand white rabbit via an angiographic catheter, and detected in magnetic resonance images of the kidney. (c) 2005 Elsevier B.V. All rights reserved.
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