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Biomemory device composed of mutant azurin thin films modified by site-directed mutagenesis
- Issue Date
- Nov-2009
- Publisher
- ELSEVIER SCIENCE SA
- Keywords
- Bioelectronic device; Site-directed mutagenesis; Surface plasmon resonance; Scanning tunneling microscopy; Raman spectroscopy; Cyclic voltammetry; Nanobiochip
- Citation
- THIN SOLID FILMS, v.518, no.2, pp 682 - 687
- Pages
- 6
- Journal Title
- THIN SOLID FILMS
- Volume
- 518
- Number
- 2
- Start Page
- 682
- End Page
- 687
- ISSN
- 0040-6090
- Abstract
- A bioelectronic device composed of self-assembled mutant azurin thin films with memory function has been developed for molecular electronics. Azurin was recombined with a cysteine residue to enhance the stability of self-assembled protein on gold surface. The thin films of protein on gold substrate were investigated by surface plasmon resonance spectroscopy, scanning tunneling microscopy and Raman spectroscopy, respectively. The memory characteristics, including the "read", "write" and "erase" functions of self-assembled azurin layer, were obtained with three distinct electrical states of azurin layers by cyclic voltammetry. These results show the proposed biomemory device as a step towards the protein based nanobiochip. (C) 2009 Elsevier B.V. All rights reserved.
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Collections - College of ICT Engineering > School of Integrative Engineering > 1. Journal Articles
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