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Nanoparticle-based energy transfer for rapid and simple detection of protein glycosylation
- Authors
- Oh, Eunkeu; Lee, Dohoon; Kim, Young-Pil; Cha, Seung Youp; Oh, Doo-Beyong; Kang, Hyun Ah; Kim, Jungbae; Kim, Hak-Sung
- Issue Date
- Dec-2006
- Publisher
- WILEY-V C H VERLAG GMBH
- Keywords
- Carbohydrates; Energy transfer; Glycoproteins; Gold nanoparticles; Quantum dots
- Citation
- ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, v.45, no.47, pp 7959 - 7963
- Pages
- 5
- Journal Title
- ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Volume
- 45
- Number
- 47
- Start Page
- 7959
- End Page
- 7963
- ISSN
- 1433-7851
1521-3773
- Abstract
- (Figure Presented) Photoluminescence quenching of dextranconjugated quantum dots (dex-QDs) by gold nanoparticles conjugated with concanavalin A (conA-AuNPs) can be prevented by adding a glycoprotein, which inhibits the association of dex-QDs with conA-AuNPs (see scheme). This phenomenon can be used as an analytical tool for the detection of protein glycosylation. PL = photoluminescence. © 2006 Wiley-VCH Verlag GmbH & Co. KGaA.
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