Preparation of polymer/drug nano- and micro-particles by electrospraying
- Authors
- Park, Chul Ho; Kim, Min Young; Yoo, Ji Youn; Kim, Ki-Hyun; Lee, Jong-Chan; Lee, Jonghwi
- Issue Date
- Mar-2007
- Publisher
- WILEY-V C H VERLAG GMBH
- Keywords
- electrospraying; nanoparticles
- Citation
- MACROMOLECULAR SYMPOSIA, v.249, pp 116 - 119
- Pages
- 4
- Journal Title
- MACROMOLECULAR SYMPOSIA
- Volume
- 249
- Start Page
- 116
- End Page
- 119
- URI
- https://scholarworks.bwise.kr/cau/handle/2019.sw.cau/57552
- DOI
- 10.1002/masy.200750319
- ISSN
- 1022-1360
1521-3900
- Abstract
- The surface energy control capability of electrohydrodynamic force provides electrospraying with various potential advantages such as simple particle size control, mono-dispersity, high recovery, and mild processing conditions. Herein, particle fabrication of biodegradable polymers using electrospraying was developed. The major processing parameters such as the conductivity of spraying liquids, flow rate, etc., were examined to obtain the successful apparatus configuration of electrospraying. The choice of a consolidation medium was critical in obtaining well-dispersed nanoparticles. When triphenylphosphate aqueous solution was employed as a consolidation medium, its concentration was not an effective parameter to control the aggregation of primary particles. When organic solvents were employed, the processing windows of electrospraying were relatively narrow than water-based systems.
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Collections - College of Engineering > School of Chemical Engineering and Material Science > 1. Journal Articles
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