An alternative miRISC targets a cancer-associated coding sequence mutation in FOXL2 (vol 39, e103304, 2020)open access
- Authors
- Shin, Eunkyoung; Jin, Hanyong; Suh, Dae-Shik; Luo, Yongyang; Ha, Hye-Jeong; Kim, Tae Heon; Hahn, Yoonsoo; Hyun, Seogang; Lee, Kangseok; Bae, Jeehyeon
- Issue Date
- Aug-2021
- Publisher
- WILEY
- Keywords
- allelic imbalance; Argonaute3; DHX9; metastasis; miR-1236
- Citation
- EMBO JOURNAL, v.40, no.16
- Journal Title
- EMBO JOURNAL
- Volume
- 40
- Number
- 16
- URI
- https://scholarworks.bwise.kr/cau/handle/2019.sw.cau/57568
- DOI
- 10.15252/embj.2021108163
- ISSN
- 0261-4189
1460-2075
- Abstract
- The authors note that P values presented in the original Fig 1A and Appendix Fig S1A were not assessed using a proper statistical analysis method. In contrast to the initially employed two-group t-test, a one-sample one-tailed t-test is appropriate here, as the basic null hypothesis is that the proportion of MT FOXL2 mRNA in each AGCT patient is lower than WT {H0: WT (%)>MT(%) }. New p values are presented in the corrected Fig 1A and Appendix Fig S1A, which are P<0.00001 and P<0.05, respectively. These revised P values did not affect the conclusion drawn. 2021 The Authors The EMBO Journal 40: e108163 | 2021 1 of 1. © 2021 EMBO.
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- Appears in
Collections - College of Pharmacy > School of Pharmacy > 1. Journal Articles
- College of Natural Sciences > Department of Life Science > 1. Journal Articles
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